Depression and Antidepressants Essay -- Chemistry Depression Papers

f alloff and AntidepressantsSpecific entirelyy the serotonergic possibility and the work of ProzacThe cause of clinical belief has long been a mystery story to physicians and researchers. Many different theories down been proposed, but no definitive prove has been put forth. However, around of what we know about clinical depression stems from the results of sure doses which urinate been successful in treating the clinically depressed. These anti--depressants have led to the self-confidence that depression is most likely due to a chemical instability (of neurotransmitters) which somehow leads to the symptoms of depression. To try and write a constitution on all the theories of depression would be endless, as would be a study on all the different types of anti-depressants. Therefore I have tried to emphasis my paper on the serotonin hypothesis for depression, and more specifically how the serotonergic anti-depressants have approve up this theory. Of course, Any paper on serotonin-based anti-depressants must implicate the habitual Prozac. Because of the excitement And controversy surrounding Prozac, I decided to business line most of my paper into the action of this so-called wonder drug. fluoxetine hydrocholoride is a second-generation anti-depressant which was developed and marketed as PROZAC by the drug guild Eli Lilly. This drug is increasingly being prescribed by physicians as the radical anti-depressant when a patient requires pharmacotherapy. This is mainly due to fluexotines reduced expression affects as compared with the older tricyclic anti-depressants. Fluoxetine is known to act as a selective serotonin reuptake inhibitor in brain synapses where serotonin is the neurotransmitter. However, an occupy mechanism has not born elucidated. Information about serotonin synaps... ..., June 1992, 89(6)445-446. (cited as 9) Hyman, S. E. & Nestler, E. J. The Molecular Foundations of Psychiatry. Washington Amer. Psych., 1993. (cited as 7 & 8) Nathan, R. S., Perel, J. H., Pollock, B. G. & Kupfer, D. J. The government agency of neuropharmacologic selectivity in antidepressant drug action. Journal of Clinical Psychiatry, Sept. 1990, 51(9) 367-372. Price, L. O., Charney, D. S., Goodman, W. K., Krystal, J. H., Woods, A. N. & Heninger, G. R. Clinical data on the role of serotonin in the mechanism of action of antidepressant drugs. Journal Clinical Psychiatry, April 1990, 51 44-50. (cited as 5) Richelson, E. Antidepressant and brain neurochemistry. Mayo Clinic Proc., Sept. 1990, 65(9) 227-236. Somni, R. W., Crismon, M. L. & Bowden, C. L. Fluoxetine a serotonin-specific, second-generation antidepressant, Pharmacotherapy, Jan.-Feb. 1987, 7(1) 1-15. Depression and Antidepressants Essay -- Chemistry Depression PapersDepression and AntidepressantsSpecifically the serotonergic hypothesis and the action of ProzacThe cause of Clinical depression has long been a mystery to physicians and researchers. Many different theories have been proposed, but no conclusive evidence has been put forth. However, most of what we know about depression stems from the results of certain drugs which have been successful in treating the clinically depressed. These anti--depressants have led to the assumption that depression is most likely due to a chemical imbalance (of neurotransmitters) which somehow leads to the symptoms of depression. To try and write a paper on all the theories of depression would be endless, as would be a study on all the different types of anti-depressants. Therefore I have tried to focus my paper on the serotonin hypothesis for depression, and more specifically how the serotonergic anti-depressants have backed up this theory. Of course, Any paper on serotonin-based anti-depressants must include the popular Prozac. Because of the excitement And controversy surrounding Prozac, I decided to channel most of my paper into the action of this so-called wonder drug. Fluoxetine is a second-generat ion anti-depressant which was developed and marketed as PROZAC by the drug company Eli Lilly. This drug is increasingly being prescribed by physicians as the primary anti-depressant when a patient requires pharmacotherapy. This is mainly due to fluexotines reduced side affects as compared with the older tricyclic anti-depressants. Fluoxetine is known to act as a selective serotonin reuptake inhibitor in brain synapses where serotonin is the neurotransmitter. However, an exact mechanism has not born elucidated. Information about serotonin synaps... ..., June 1992, 89(6)445-446. (cited as 9) Hyman, S. E. & Nestler, E. J. The Molecular Foundations of Psychiatry. Washington Amer. Psych., 1993. (cited as 7 & 8) Nathan, R. S., Perel, J. H., Pollock, B. G. & Kupfer, D. J. The role of neuropharmacologic selectivity in antidepressant action. Journal of Clinical Psychiatry, Sept. 1990, 51(9) 367-372. Price, L. O., Charney, D. S., Goodman, W. K., Krystal, J. H., Woods, A. N. & Heninger, G. R. Clinical data on the role of serotonin in the mechanism of action of antidepressant drugs. Journal Clinical Psychiatry, April 1990, 51 44-50. (cited as 5) Richelson, E. Antidepressant and brain neurochemistry. Mayo Clinic Proc., Sept. 1990, 65(9) 227-236. Somni, R. W., Crismon, M. L. & Bowden, C. L. Fluoxetine a serotonin-specific, second-generation antidepressant, Pharmacotherapy, Jan.-Feb. 1987, 7(1) 1-15.